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The first aim of the founders of the laboratory was to understand how proprioceptive afferents, by their actions on spinal neurons, control movement in mammals. Our interest in the motor system then extended to the operating principles of basal ganglia and to the motor strategies in healthy subjects and patients. We believe that our research work helps to understand the mechanisms underlying severe motor pathologies such as spasticity, Parkinson’s disease, apraxia... Our interest is not restricted to the motor systems and we have undertaken experimental and theoretical research on visual information processing from the retina to the cortex. Along the way, new methods have enriched our laboratory: immunohistochemistry, in vitro electrophysiology of spinal cord, kinematic analysis of upper human limb. The friendly atmosphere that prevails in the laboratory is largely due to the fact that people coming from different scientific fields are working together. Exciting research investigations are stimulated by our collaborations with laboratories in France and abroad. This environment contributes to give our junior scientists the training they deserve. They are the future of science.
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