David Dubayle

Teaching :

Research Interests :

• Cerebral and cerebellar cortices
• Thalamic sensory processes
• Oculomotor systems
• Medullary respiratory and spinal locomotor generators

Mast cell infiltration of the thalamus

Methods employed :

• Histology and Immunohistochemistry
• Transneuronal retrograde tracing of neuronal connections using virus or toxin
• Neurolucida 3D reconstruction
• Extracellular recordings on in vitro brainstem spinal cord preparations

Fluorescence microscopy of single neurone

19. DUBAYLE D. and HERON A. “Decrease of cerebral mast cell degranulation after systemic administration of lipopolysaccharide”. Inflammation Research (IF : 2,109), 61 : 1295-7.

18. ROSSIGNOL J., BOYER C., THINARD R., REMY S., DUGAST A.S., DUBAYLE D., DEY N.D., BOEFFARD F., DELECRIN J., HEYMANN D., VANDHOVE B., ANEGON I., NAVEILHAN P., DUNBAR G.L. and LESCAUDRON L (2009). “Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation”. Journal of Cellular and Molecular Medicine (IF : 4,608), 13 : 2547-58.

17. BEGHDADI W., PORCHERIE A., SCHNEIDER B., MORISSET S., DUBAYLE D., PERONET R., DY M., LOUIS J., ARRANG J.M., and MECHERI S (2009). “Histamine H(3) receptor-mediated signaling protects mice from cerebral malaria”. PLoS ONE (IF : 4,411), 4 : e6004.

16. BEGHDADI W., PORCHERIE A., SCHNEIDER B.S., DUBAYLE D., PERONET R., HUERRE M., WATANABE T., OHTSU H., LOUIS J. et MECHERI S. (2009) “Rôle de l’histamine et des récepteurs histaminiques dans la pathogénèse du paludisme”. Médecine Sciences (Paris) (IF : 0,64), 25 : 377-381.

15. BEGHDADI W., PORCHERIE A., SCHNEIDER B., DUBAYLE D., PERONET R., HUERRE M., WATANABE T., OHTSU H., LOUIS J. and MECHERI S. (2008). “Inhibition of histiamine-mediated signaling confers significant protection against severe malaria in mouse models of disease”. Journal of Experimental Medicine (IF : 14,776), 205 : 395-408.

14. DUBAYLE D., SERVIERE J. and MENETREY D (2007). “The effects of viscero-somatic interactions on thalamic mast cell recruitment in cystitic rats”. Journal of Neuroimmunology (IF : 2,901), 190 : 18-27.

13. UGOLINI G., KLAM F., DOLDAN DANS M., DUBAYLE D., BRANDI A.M., BÜTTNER-ENNEVER J. and GRAF W. (2006) “Horizontal eye movement networks in primates as revealed by retrograde transneuronal transfer of rabies virus : differences in monosynaptic input to « slow » and « fast » abducens motoneurons”. Journal of Comparative Neurology (IF : 3,774), 498 : 762-85.

12. DUBAYLE D., MALISSIN I. and MENETREY D. (2005) “Differential effects of two analgesic drugs, morphine chlorhydrate and acethylsalicylic acid, on thalamic mast cell numbers in rat”. Journal of Neuroimmunology (IF : 2,901), 169 : 106-15.

11. DUBAYLE D., SERVIERE J. and MENETREY D. (2005) “Evidence for serotonin influencing the thalamic infiltration of mast cells in rat”. Journal of Neuroimmunology (IF : 2,901), 159 : 20-30.

10. MENETREY D. and DUBAYLE D. (2003) “A one-step dual-labeling method for antigen detection in mast cells”. Histochemistry and Cell Biology (IF : 4,727), 120 : 435-442.

9. SERVIERE J., DUBAYLE D. and MENETREY D. (2003) “Increase of rat medial habenular mast cell numbers by systemic administration of cyclophosphamide”. Toxicology Letters (IF : 3,581), 145 : 143-152.

8. GRANTYN A., BRANDI A.M., DUBAYLE D., GRAF W., UGOLINI G., HADJIDIMITRAKIS K. and MOSCHOVAKIS A.K. (2002) “Density gradients of trans-synaptically labeled collicular neurons after injections of rabies virus in the lateral rectus muscle of rhesus monkey”. Journal of Comparative Neurology (IF : 3,774), 451 : 346-361.

7. BUHOT M.C., DUBAYLE D., MALLERET G., JAVERZAT S. and SEGU L. (2001) “Exploration, anxiety and spatial memory in transgenic anophtalmic mice”. Behavioural Neurosciences (IF : 2,481), 115 : 455-467.

6. ROUSSEAU B., DUBAYLE D., SENNLAUB F., JEANNY J.C., COSTET P., BIKFALVI A., and JAVERZAT S. (2000) “Neural and Angiogenic defects in eyes of transgenic mice expressing a dominant-negative FGF receptor in the pigment cells”. Experimental Eye Research (IF : 2,817), 71 : 395-404.

5. DUBAYLE D. and VIALA D. (1998) “ Effects of CO2 and H+ on spinal respiratory activity in vitro”. Brain Research bulletin (IF : 2,498), 45 : 83-87.

4. DUBAYLE D. and VIALA D. (1998) “Entrainment of the medullary generator by electrical stimulations in the cervical grey matter from in vitro preparations of newborn rats”. Neuroscience letters (IF : 2,055), 248 : 204-208.

3. DUBAYLE D. and VIALA D. (1996) “Localisation of the spinal respiratory rhythm generator by an in vitro electrophysiological approach”. NeuroReport (IF : 1,822), 7 : 1175-1180.

2. DUBAYLE D. and VIALA D. (1996) “Interactions between medullary and spinal respiratory rhythm generators in the in vitro brainstem spinal cord preparations from newborn rats”. Experimental Brain Research (IF : 2,817), 109 : 1-8.

1. DUBAYLE D. et VIALA D. (1993) “Possible existence of spinal inspiratory activity in the in vitro brain stem-spinal cord preparation from newborn rats”. C.R. Acad. Sci. III (IF : 1,603), 316 : 1458-1462.

Contact Information :

Biomedical unit - 1950

. Laboratory of Neurophysics and Physiology - CNRS UMR 8119
Paris Descartes University - Biomedical unit
45 Rue des Saints Pères
75270 Paris Cedex 06
France

. Tel : Office +33 (0) 1 42 86 22 82
Tel : Fax +33 (0) 1 49 27 90 62

. Email : david.dubayle parisdescartes.fr